Smaller cardiac cell size and reduced extra-cellular collagen might be...
Purpose: To test the hypothesis that cardiac morphologic differences between Ames dwarf and wild-type littermates might correlate with the increased longevity observed in the Ames dwarf mice.Methods:...
View ArticleIdentification and Molecular Characterization of a New Member of the...
The peritrophic membrane (PM) plays an important role in protecting insects. The PM proteins are important to determinate the formation and function of the PM. A new PM protein, named Lsti99, was...
View ArticleIncreased Proliferation and Analysis of Differential Gene Expression in Human...
Multipotent mesenchymal stromal cells (MSCs) from Wharton's jelly (WJ) of umbilical cord bear higher proliferation rate and self-renewal capacity than adult tissue-derived MSCs and are a primitive...
View ArticleBP1, an Isoform of DLX4 Homeoprotein, Negatively Regulates BRCA1 in Sporadic...
Introduction: Several lines of evidence point to an important role for BP1, an isoform of DLX4 homeobox gene, in breast carcinogenesis and progression. BRCA1 is a well-known player in the etiology of...
View ArticleAlpha-Calcitonin Gene-Related Peptide Can Reverse The Catabolic Influence Of...
Background and purpose: A linkage between the neurotransmitter alpha-calcitonin gene-related peptide (alpha-CGRP) and particle-induced osteolysis has been shown previously. The suggested...
View ArticleCircling behavior developed in Dmp1 null mice is due to bone defects in the...
With age, there is a progressive loss of body balance function. Yet, the potential influence of osteoporosis on body balance is largely unknown. Dentin matrix protein 1 (DMP1) is highly expressed in...
View ArticleMyocardial deletion of Smad4 using a novel α skeletal muscle actin Cre...
SMAD4 acts as the converging point for TGFβ and BMP signaling in heart development. Here, we investigated the role of SMAD4 in heart development using a novel α skeletal muscle actin Cre recombinase...
View ArticleActivity and interactions of antibiotic and phytochemical combinations...
In this study the in vitro activities of seven antibiotics (ciprofloxacin, ceftazidime, tetracycline, trimethoprim, sulfamethoxazole, polymyxin B and piperacillin) and six phytochemicals...
View ArticleAnterior Visceral Endoderm SMAD4 Signaling Specifies Anterior Embryonic...
SMAD4 serves as a common mediator for signaling of TGF-β superfamily. Previous studies illustrated that SMAD4-null mice die at embryonic day 6.5 (E6.5) due to failure of mesoderm induction and...
View ArticleConstruction of cDNA library and preliminary analysis of expressed sequence...
In this study we successfully constructed a full-length cDNA library from Siberian tiger, Panthera tigris altaica, the most well-known wild Animal. Total RNA was extracted from cultured Siberian tiger...
View ArticleDebate on GMOs Health Risks after Statistical Findings in Regulatory Tests
We summarize the major points of international debate on health risk studies for the main commercialized edible GMOs. These GMOs are soy, maize and oilseed rape designed to contain new pesticide...
View ArticleAberrant Cytoplasm Localization and Protein Stability of SIRT1 is Regulated...
SIRT1, an NAD-dependent histone/protein deacetylase, has classically been thought of as a nuclear protein. In this study, we demonstrate that SIRT1 is mainly localized in the nucleus of normal cells,...
View ArticleAntennal expression pattern of two olfactory receptors and an odorant binding...
Odor-detection in the malaria mosquito Anopheles gambiae involves large families of diverse proteins, including multiple odorant binding proteins (AgOBPs) and olfactory receptors (AgORs). The...
View ArticleGene Expression Profiling of Skeletal Muscle of Nursing Piglets
To gain insight into the regulation mechanism associated with the rapid gain in skeletal muscle during neonatal period, gene expression profiles of skeletal muscle of nursing pigs was investigated...
View ArticleComparative Analysis of Cytotoxic T Lymphocyte Response Induced by Dendritic...
The choice of the tumor antigen preparation used for dendritic cell (DC) loading is important for optimizing DC vaccines. In the present study, we compared DCs pulsed with hepatocellular carcinoma...
View ArticleMechanical Forces Used for Cell Fractionation Can Create Hybrid Membrane...
The ability to understand the inner works of the cell requires methods for separation of intracellular membrane-enclosed compartments. Disruption of the plasma membrane (PM) by mechanical forces to...
View ArticleNuclear factor-Y (NF-Y) regulates transcription of mouse Dmrt7 gene by...
Dmrt7, a member of the Dmrt family of genes, is required for spermatogenesis. However, promoter functions of the gene Dmrt7 remain unknown. We have cloned and characterized the proximal promoter...
View ArticleMechanism of Processive Movement of Monomeric and Dimeric Kinesin Molecules
Kinesin molecules are motor proteins capable of moving along microtubule by hydrolyzing ATP. They generally have several forms of construct. This review focuses on two of the most studied forms:...
View ArticleThe application of Toll like receptors for cancer therapy
Toll-like receptor (TLR) proteins play key roles in immune responses against infection. Using TLR proteins, host can recognize the conserved molecular structures found in pathogens called...
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